Cell-mediated immune response following Mycoplasma pneumoniae infection in man. II. Leucocyte migration inhibition.

  • 1 May 1974
    • journal article
    • Vol. 17  (1) , 43-9
Abstract
By the use of the leucocyte migration inhibition assay a cell-mediated immune response to Mycoplasma pneumoniae was demonstrated in seven out often patients examined 3–6 weeks after onset of lower respiratory-tract illness associated with M. pneumoniae infection. Six months after onset of illness M. pneumoniae-induced migration inhibition was only demonstrable in one out of four cases with a positive migration inhibition assay during the early period after infection. Among four other cases examined 1 year after infection inhibition of leucocyte migration was also demonstrable in only one case. The migration of leucocytes from eight healthy blood donors was not inhibited by M. pneumoniae antigen.