EXPERIMENTAL BOTRYOMYCOSIS PRODUCED BY PSEUDOMONAS AERUGINOSA

Abstract
Guinea-pigs intratesticularly challenged with small doses of Pseudomonas aeruginosa developed local abscesses with actinomycetoid granules measuring up to 300 μm in diameter; metastatic foci of infection in the lungs also contained granules. An eosinophilic shell supporting a crown of eosinophilic clubs is a noteworthy characteristic of the young granules produced by all three of the strains of Ps. aeruginosa studied. Granules were visible as early as 4 days after the inoculation of 0·1-ml doses of suspensions containing 104 bacteria per ml. No granules were produced in the mice challenged intraperitoneally.

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