Effects of topically potent glucocorticoids on human diploid fibroblasts in vitro
- 1 July 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 97 (1) , 69-75
- https://doi.org/10.1111/j.1365-2133.1977.tb15430.x
Abstract
A wide range of concentrations of both cortisol and a topically more potent synthetic derivative, fluocinolone acetonide, did not inhibit the growth of cultured human skin fibroblasts; fluocinolone acetonide produced a slight increase in the growth rate. Both steroids had a transient stimulatory effect on fibroblasts, promoting an earlier entry into the period of DNA synthesis (S) which was also accompanied by a substantial increase in the length of S.This publication has 7 references indexed in Scilit:
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