The preparation of porphyrin S-411 (dehydrocoproporphyrin) and harderoporphyrin from protoporphyrin IX
- 1 March 1981
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 59 (5) , 779-785
- https://doi.org/10.1139/v81-113
Abstract
Protoporphyrin IX dimethyl ester has been converted into the two 2,4-positional isomers bearing hydroxyethyl and methoxycarbonylvinyl side chains. The 4-(2-hydroxyethyl) group was extended to a methoxycarbonylethyl group to give the tetramethyl ester of porphyrin S-411 (2-methoxycarbonylvinyl-4-methoxycarbonylethyldeuteroporphyrin dimethyl ester). On the other hand reduction of the 4-methoxycarbonylvinyl to the corresponding methoxycarbonylethyl group and dehydration of the 2-(2-hydroxyethyl) to a vinyl side chain gave the trimethyl ester of harderoporphyrin (2-vinyl-4-methoxycarbonylethyldeuteroporphyrin dimethyl ester).This publication has 1 reference indexed in Scilit:
- Pyrroles and related compounds—XXXVITetrahedron, 1976