MOXALACTAM AS SINGLE-AGENT PROPHYLAXIS IN THE PREVENTION OF WOUND-INFECTION FOLLOWING COLON SURGERY

  • 1 January 1987
    • journal article
    • research article
    • Vol. 101  (1) , 15-19
Abstract
A single agent systemic antibiotic (moxalactam) when used prophylactically in patients undergoing colon surgery was associated with a wound infection rate comparable to that achieved by a combination of oral neomycin and intravenous metronidazole. The data obtained demonstrated that the reduced infection rate was not the result of a reduction in the bacterial content of the colon alone but due to the prophylactic agents used for elective colon surgery.