Risks of Correcting the Risks of Coronary Disease and Stroke with Drugs
- 4 February 1982
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 306 (5) , 297-298
- https://doi.org/10.1056/nejm198202043060511
Abstract
Insufficient concern has been expressed about the development and incidence of unexpected adverse reactions to drugs given prophylactically over many years in attempts to reduce the risks of coronary and cerebrovascular diseases in predisposed but otherwise healthy persons. It has been assumed that the risks associated with drug treatment are low because they relate mostly to predictable minor side effects or idiosyncratic reactions, but when reactions include increased morbidity and mortality, a reappraisal is necessary; the risks involved in correcting risk must be compared with the risk of the disease in question.It may seem to be stating the obvious . . .Keywords
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