Modeling for Lesch‐Nyhan Disease by Gene Targeting in Human Embryonic Stem Cells
Open Access
- 1 July 2004
- journal article
- letter
- Published by Oxford University Press (OUP) in The International Journal of Cell Cloning
- Vol. 22 (4) , 635-641
- https://doi.org/10.1634/stemcells.22-4-635
Abstract
STEM CELLS, a peer reviewed journal published monthly, provides a forum for prompt publication of original investigative papers and concise reviews. STEM CELLS is read and written by clinical and basic scientists whose expertise encompasses the rapidly expanding fields of stem and progenitor cell biology. STEM CELLS welcomes original articles and concise reviews describing basic laboratory investigations of stem cells and the translation of their clinical aspects of characterization and manipulation from the bench to patient care. The journal covers all aspects of stem cells embryonic stem cells/induced pluripotent stem cells; tissue-specific stem cells; stem cell technology: epigenetics, genomics, proteomics, and metabonomics; cancer stem cells; translational and clinical research; and regenerative medicine.Keywords
This publication has 18 references indexed in Scilit:
- Homologous recombination in human embryonic stem cellsNature Biotechnology, 2003
- A map of human genome sequence variation containing 1.42 million single nucleotide polymorphismsNature, 2001
- Neurotransmitter changes in the pathophysiology of Lesch–Nyhan syndromeBrain & Development, 2000
- Gene targeting is enhanced in human cells overexpressing hRAD51Gene Therapy, 1999
- Gene Targeting in Human Cells Without Isogenic DNAScience, 1999
- Embryonic Stem Cell Lines Derived from Human BlastocystsScience, 1998
- Mouse models of human disease. Part II: recent progress and future directions.Genes & Development, 1997
- Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs.Proceedings of the National Academy of Sciences, 1992
- Targeting of the creating kinase M gene in embryonic stem cells using isogenic and nonisogenic vectorsNucleic Acids Research, 1992
- The Lesch-Nyhan syndrome: clinical, molecular and genetic aspectsTrends in Genetics, 1988