A structural basis for four distinct elution profiles on concanavalin A – Sepharose affinity chromatography of glycopeptides

1 January 1979

journal article
research article
Published by Canadian Science Publishing in Canadian Journal of Biochemistry

Vol. 57 (1) , 83-96
https://doi.org/10.1139/o79-011

Abstract

Affinity chromatography of 12 14C-acetylated glycopeptides on Concanavalin A (Con A)-Sepharose was studied. A minimum of 2 interacting mannose residues are apparently required for binding to ConA-Sepharose; the residues linked to those mannoses can either strengthen or weaken binding.