Antibiotic Medication of Chickens Experimentally Infected with Mycoplasma gallisepticum and Escherichia coli

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Abstract
The prophylactic and therapeutic effectiveness of chlortetracyline (CTC) and oxytetracycline (OTC), potentiated by TPA or a low C and P ration, was evaluated in chickens experimentally infected with virulent strains of M. gallisepticum and E. coli. The performance of the un-inoculated control birds from CRD-free stock was superior to that of inoculated-treated birds and inoculated control birds. Medication of inoculated birds considerably reduced by severity and extent of gross pathological involvement. Potentiated CTC was more effective than similar levels of nonpotentiated CTC in decreasing the severity of CRD. In comparative evaluation of CTC, OTC and CTC plus OTC, there were only slight inter-treatment differences when similar levels were used: CTC and CTC plus OTC were slightly superior to OTC.