Role of the H-2 Complex in Preimplantation Mouse Embryo Development

Abstract
The H-2 complex influences early mouse embryo development. Slow development was associated with the H-2k haplotype. By the use of congenic strains, it was clearly demonstrated that gene(s) in the H-2 complex affect the time of the first cleavage division and the rate of subsequent preimplantation development.

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