Differentiating Alzheimer’s Disease and Frontotemporal Dementia: Receiver Operator Characteristic Curve Analysis of Four Rating Scales

Publisher Website
Google Scholar
Abstract
Alzheimer’s disease and frontotemporal dementia are two of the most common types of degenerative dementia. In conjunction with a complete neuropsychiatric examination, the Executive Interview©, Mini-Mental State Exam, Alzheimer’s Disease Scale, Pick’s Disease Scale and the Informant-Based Questionnaire have been used to distinguish between these two disorders on clinical grounds. In a review of two studies, scores from these rating scales are subjected to receiver operator characteristic curve analysis to determine the cut-off value for each scale which yields the highest sensitivity and specificity with regard to differentiating between Alzheimer’s disease and frontotemporal dementia. Finally, the Informant-Based Questionnaire is discussed and compared to each rating scale to demonstrate the important features and limitations of each.

This publication has 6 references indexed in Scilit: