Defective Protein C in Uraemia
- 1 January 1987
- journal article
- research article
- Published by S. Karger AG in Blood Purification
- Vol. 5 (1) , 29-32
- https://doi.org/10.1159/000169453
Abstract
Protein C activity and antigen levels were determined in 10 haemodialysis patients and 10 healthy controls matched for age and sex. Markedly decreased protein C activity was found whereas protein C antigen level was normal in uraemics. This finding, together with our recent observation that plasma protein C activity is partly normalised during haemodialysis, lead us to suggest the presence of one or more inhibitors of protein C activity in plasma from patients with uraemia.Keywords
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