Survival of Mice Receiving Melanoma Transplants Is Promoted by Hydroquinone
- 25 April 1980
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 208 (4442) , 408-410
- https://doi.org/10.1126/science.7367868
Abstract
In BALB/c female mice with melanoma transplants, the incidence of "takes" is decreased and survival is increased by hydroquinone, a melanocytolytic agent. The mechanism of drug action is suggested to be via DNA. The significant and high degree of positive response to hydroquinone treatment in vivo is encouraging for the clinical management of melanoma with melanocytolytic agents.Keywords
This publication has 13 references indexed in Scilit:
- Hydroxyanisole‐induced regression of the Harding‐Passey melanoma in miceThe Journal of Pathology, 1977
- Mechanism of Depigmentation by HydroquinoneJournal of Investigative Dermatology, 1974
- 352. Note: Conservatism of the Approximation Σ(O - E) 2 /E in the Logrank Test for Survival Data or Tumor Incidence DataPublished by JSTOR ,1973
- PART I. ANALYSIS OF PRESENTING FEATURES OF PROGNOSTIC IMPORTANCEBritish Journal of Haematology, 1973
- Asymptotically Efficient Rank Invariant Test ProceduresJournal of the Royal Statistical Society. Series A (General), 1972
- Evaluation of the Toxicity of the Monoethyl Ether of Hydroquinone for Mammalian Melanocytes and Melanoma CellsJournal of Investigative Dermatology, 1971
- Experimentelle Depigmentierung der Meerschweinchenhaut durch selektiv toxische Wirkung von Hydrochinon-mono thyl ther auf die MelanocytenArchives of Dermatological Research, 1969
- Selective Action of Mercaptoethylamines on Melanocytes in Mammalian SkinArchives of Dermatology, 1968
- Depigmentation of Skin with 4-Isopropylcatechol, Mercaptoamines, and other Compounds*Journal of Investigative Dermatology, 1968
- The Influence of Certain Hormones and Chemicals on Mammalian Pigment Cells**From the Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.Journal of Investigative Dermatology, 1966