Ispaghula Husk May Relieve Gastrointestinal Symptoms in Ulcerative Colitis in Remission
- 1 January 1991
- journal article
- clinical trial
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 26 (7) , 747-750
- https://doi.org/10.3109/00365529108998594
Abstract
The efficiency of ispaghula husk in relieving gastrointestinal symptoms in patients with ulcerative colitis in remission was studied in a placebo-controlled trial running for 4 months. Twenty-nine patients (81%) completed the trial; four withdrew after colitis relapse (three while receiving placebo). Grading of symptoms judged ispaghula to be consistently superior to placebo (p less than 0.001) and associated with a significantly higher rate of improvement (69%) than placebo (24%) (p less than 0.001). The results show that ispaghula can be helpful in the management of gastrointestinal symptoms in quiescent ulcerative colitis.Keywords
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