Towards a new age of virtual ADME/TOX and multidimensional drug discovery
- 1 January 2000
- journal article
- review article
- Published by Springer Nature in Molecular Diversity
- Vol. 5 (4) , 255-275
- https://doi.org/10.1023/a:1021376212320
Abstract
No abstract availableKeywords
This publication has 97 references indexed in Scilit:
- Direct Evidence for Peptide Transporter (PepT1)-Mediated Uptake of a Nonpeptide Prodrug, ValacyclovirBiochemical and Biophysical Research Communications, 1998
- In vitro mutagenicity and genotoxicity study of a number of short-chain chlorinated hydrocarbons using the micronudeus test and the alkaline single cell gel electrophoresis technique (Comet assay) in human lymphocytes: a structure–activity relationship (QSAR) analysis of the genotoxic and cytotoxic potentialMutagenesis, 1998
- Enhanced Detoxication Due to Distributive Catalysis and Toxic Thresholds: A Kinetic AnalysisBiochemistry, 1997
- Use of In Vitro and In Vivo Data to Estimate the Likelihood of Metabolic Pharmacokinetic InteractionsClinical Pharmacokinetics, 1997
- An approach to QSAR of 16-substituted pregnenolones as microsomal enzyme inducersEuropean Journal of Drug Metabolism and Pharmacokinetics, 1996
- Correlation of Drug Absorption with Molecular Surface PropertiesJournal of Pharmaceutical Sciences, 1996
- Identification of Common Functional Configurations Among MoleculesJournal of Chemical Information and Computer Sciences, 1996
- Structural features of the uniporter/symporter/antiporter superfamilyProtein Science, 1995
- The Human Hepatic Cytochromes P450 Involved in Drug MetabolismCritical Reviews in Toxicology, 1992
- High-Resolution Structures of Photosynthetic Reaction CentersAnnual Review of Biophysics, 1991