Carbon–carbon bond formation at the C-4 position of an azetidin-2-one ring by intermolecular radical coupling reactions: a route to tribactams
- 1 January 1994
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 4,p. 441-442
- https://doi.org/10.1039/c39940000441
Abstract
The β-lactam 4 was linked to the enones 8–10 using a radical reaction mediated by tri-n-butyltin hydride to give the 2,6-disubstituted cyclohexanones 11–16, respectively: 13 was converted into the protected tribactam 18 in two steps.Keywords
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