Science commentary: Why albumin may not work
- 25 July 1998
- Vol. 317 (7153) , 240
- https://doi.org/10.1136/bmj.317.7153.240
Abstract
Starling's principle is often represented as the leakage of fluids from the arterial end of capillaries, where the hydrostatic pressure is greater than the oncotic pressure (derived from the plasma proteins), and the reabsorption of fluid into the venous end, where the oncotic pressure exceeds the hydrostatic pressure. A small excess of fluid in the interstitial space—when filtration from the capillaries is greater than reabsorption—is dealt with by lymphatic drainage from the interstitial space. The rationale for giving albumin solutions rather than crystalloid solutions in cases of hypovolaemic shock is that fluid reabsorption …Keywords
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