Routine Morphine Infusion in Preterm Newborns Who Received Ventilatory Support
Open Access
- 12 November 2003
- journal article
- clinical trial
- Published by American Medical Association (AMA) in JAMA
- Vol. 290 (18) , 2419-2427
- https://doi.org/10.1001/jama.290.18.2419
Abstract
Morphine has been one of the most frequently used drugs to relieve pain in many age groups. Nevertheless, debate continues about whether morphine and analgesic therapy should serve as standard of care for preterm newborns who have received ventilatory support,1 despite the recognition that all preterm neonates feel pain.Keywords
This publication has 50 references indexed in Scilit:
- Are postoperative pain instruments useful for specific groups of vulnerable infants?Clinics in Perinatology, 2002
- Cardiovascular effects of an intravenous bolus of morphine in the ventilated preterm infantArchives of Disease in Childhood: Fetal & Neonatal, 2000
- Morphine clearance and effects in newborn infants in relation to gestational ageClinical Pharmacology & Therapeutics, 2000
- Narcotic analgesia for ventilated newborns: Are placebo-controlled trials ethical and necessary?The Journal of Pediatrics, 1999
- Randomised double blind trial of morphine versus diamorphine for sedation of preterm neonatesArchives of Disease in Childhood: Fetal & Neonatal, 1998
- Hemodynamic effects of intravenous morphine infusion in ventilated preterm babiesEarly Human Development, 1997
- Respiratory Effects of Intravenous Morphine Infusions in Neonates, Infants, and Children After Cardiac SurgeryAnesthesia & Analgesia, 1993
- Pharmacokinetics of morphine infusion in premature neonates.Archives of Disease in Childhood, 1993
- Modulation of brain development by morphine: Effects on central motor systems and behaviorPeptides, 1985
- Respiratory sensitivity of the newborn infant to meperidine and morphineClinical Pharmacology & Therapeutics, 1965