Effects of semistarvation on transintestinald-glucose transport andd-glucose uptake in brush border and basolateral membranes of rat enterocytes

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Abstract
The present work shows that semistarvation (8–10 g of food for 10 days) increases netd-glucose, Na+ and water transport in the everted and perfused rat jejunum. A lincar and positive correlation between cell sugar concentration and transport was found in control and semistarved rats, but the phenomenon was more relevant only in semistarved animals. Membrane vesicle experiments showed that semistarvation increases sugar overshoot only in brush border membrane vesicles, while this situation does not occur in basolateral membrane vesicles. The effect of partial food deprivation seems to enhance net sugar transport by mereasing sugar entry across the apical membrane of enterocytes.