Effects of chlordiazepoxide, amitriptyline, imipramine, and their combinations on avoidance behaviour in mice
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 59 (2) , 151-155
- https://doi.org/10.1007/bf00427749
Abstract
Chlordiazepoxide, imipramine, and amitriptyline, given alone or in combination, were tested in mice subjected to 5 daily 100-trial avoidance sessions in the shuttle-box. When the drugs were given alone, chlordiazepoxide and the lower doses of imipramine facilitated avoidance behaviour. The higher doses of the two antidepressants impaired avoidance behaviour. Mixtures of chlordiazepoxide and imipramine produced some facilitating effects, while depressant effects prevailed in the chlordiazepoxide-amitriptyline combinations.This publication has 17 references indexed in Scilit:
- Facilitating effects of chlordiazepoxide on locomotor activity and avoidance behaviour of reserpinized micePsychopharmacology, 1978
- Clinical Response to Amitriptyline and Chlordiazepoxide-Amitriptyline (Limbitrol®) in Anxiety-Depressive States: A Double-Blind StudyPsychosomatics, 1973
- Propranolol and chlordiazepoxide on experimentally induced conflict and shuttle box performance in rodentsPsychopharmacology, 1973
- Effects of chlorpromazine and chlordiazepoxide on discriminated lever-press avoidance behavior and intertrial responding in micePsychopharmacology, 1972
- Persistence of Dose Related Behaviour in MiceNature, 1971
- Enhancement of amphetamine-induced stereotyped behavior by benzodiazepinesEuropean Journal of Pharmacology, 1971
- Drug Effects and Learning and Memory ProcessesPublished by Elsevier ,1971
- Genetic Aspects of Learning and Memory in MiceScience, 1969
- Effects of chlordiazepoxide on the acquisition of avoidance learning and its transfer to the normal state and other drug conditionsPsychopharmacology, 1966
- The Pharmacology of Imipramine and Related AntidepressantsPublished by Elsevier ,1966