Non-human primate platelets and arterial tissue cannot convert preformed [14C]lanosterol into[14C]cholesterol in vivo
- 15 July 1976
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 158 (1) , 157-159
- https://doi.org/10.1042/bj1580157
Abstract
In contrast with the prevailing view, we report the inability of non-human primate platelets or arterial tissue to complete the biosynthesis of [14C]cholesterol from [14C]mevalonic acid in vitro or in vivo, or from performed [14C]lanosterol in vivo. The latter observation suggests that these tissues lack one or more components of the methyl sterol demethylase system.This publication has 5 references indexed in Scilit:
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