Surveillance of respiratory virus infections among Alaskan Eskimo children

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Abstract
During the winter of 1966, surveillance of acute virus-associated respiratory disease was undertaken among Eskimo children resident at Bethel, Alaska. Combined sero-logic and isolation studies revealed evidence of viral association in 48 (75%) of the cases. A respiratory syncytial virus outbreak and a mixed influenza A2 and B epidemic occurred during the study period. Evidence of simultaneous infection with influenza A2 and B viruses was obtained in 13 children. Other isolations included parainfluenza virus types 1 and 3, adenovirus types 2 and 5, rhinovirus, and herpes simplex virus. Virus transport medium consisting of tryptose phosphate broth with 0.5% gelatin and 1% chicken serum proved suitable for isolation of respiratory syncytial virus, despite one cycle of freeze-thaw with storage at [long dash]70 C for as long as ten days prior to attempts at viral isolation.

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