Methotrexate pneumonitis in a psoriatic
- 1 July 1975
- journal article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 93 (1) , 107-110
- https://doi.org/10.1111/j.1365-2133.1975.tb06485.x
Abstract
A life-threatening respiratory disease, characterized by fever, cough, dyspnoea, cyanosis and wide-spread bilateral pulmonary infiltrates, developed in a 40-year-old patient receiving intermittent methotrexate therapy for psoriasis. Blood eosinophilia accompanied the illness. A prominent feature in the clinical picture was a discrepancy between auscultatory findings and the pronounced changes in the chest X-ray. Systemic corticosteroids produced rapid improvement. It is suggested that the pulmonary syndrome represents a hypersensitivity reaction.Keywords
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