2,5-Unsubstituted pyrrolidines from formaldehyde and amino acids through in situ azomethine-ylide 1,3-dipolar cycloaddition to alkenes
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 22,p. 1566-1567
- https://doi.org/10.1039/c39850001566
Abstract
Formaldehyde and α-amino acids such as sarcosine and glycine react with alkenes to give N-Me and N-H Pyrrolidines via in situ generated azomethine-yields.Keywords
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