Ethanol Alters Kinetic Characteristics and Function of Striatal Morphine Receptors
- 1 August 1981
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 37 (2) , 518-521
- https://doi.org/10.1111/j.1471-4159.1981.tb00487.x
Abstract
Morphine was shown to promote dopamine (DA) synthesis and release in mouse striatum, but mice rendered tolerant and dependent on ethanol were found to be less responsive to morphine's effects on striatal DA metabolism than control animals. Ethanol feeding also produced a change in the affinity of striatal “opiate” receptors for [3H]dihydromorphine, and these ethanol‐induced receptor changes may be responsible for the altered biological effect of morphine.Keywords
This publication has 27 references indexed in Scilit:
- Receptor‐Mediated Dopaminergic Function After Ethanol WithdrawalAlcohol, Clinical and Experimental Research, 1980
- A High Performance Liquid Chromatography Method for Measuring Brain Dihydroxyphenylalanine Levels and Dopamine Synthesis RatesJournal of Neurochemistry, 1980
- Regulation of nigrostriatal and tuberoinfundibular-hypophyseal dopaminergic neuronsProgress in Neurobiology, 1979
- DETERMINATION OF CATECHOLAMINES IN RAT BRAIN PARTS BY REVERSE‐PHASE ION‐PAIR LIQUID CHROMATOGRAPHYJournal of Neurochemistry, 1978
- Reduction of striatal dopamine release during an ethanol withdrawal syndromeJournal of Neurochemistry, 1977
- Enkephalin receptors on dopaminergic neurones in rat striatumNature, 1977
- Improved Recovery of Morphine from Biological Tissues Using Siliconized GlasswareJournal of Pharmaceutical Sciences, 1977
- Feedback loop or output pathway in striato-nigral fibres?Nature, 1977
- Narcotic dependence, narcotic action and dopamine receptorsLife Sciences, 1975
- THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONSAnnals of the New York Academy of Sciences, 1949