Determination of Xenopus Index and Haemolytic Index in Fruits of Sapindus Mukorossi Gaertn. (Sapindaceae) and Seeds of Entada Scandens Benth. (Mimosaceae)

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Abstract
Two drugs, known from the Burmese and Indian folk medicines, the fruits of Sapindus mukorossi and the seeds from Entada scandens, were examined for their effect on Xenopus larvae. As a comparative test the haemolytic index of the drugs was also determined. The investigations showed that parts of both drugs contained substances which were toxic for Xenopus larvae and which haemolysed blood. The fruit wall from Sapindus mukorossi and the seed kernel from Entada scandens had a Xenopus index of approximately 7,000 and 400 respectively. The corresponding haemolytical indexes were approximately 7,000 and 150.

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