RTX Toxin Actin Cross-Linking Activity in Clinical and Environmental Isolates of Vibrio cholerae
- 1 July 2007
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 45 (7) , 2289-2292
- https://doi.org/10.1128/jcm.00349-07
Abstract
Vibrio cholerae strains from diverse O-antigen groups were evaluated for RTX toxin actin cross-linking activity. This study demonstrates that the actin cross-linking domain sequence is present within rtxA in the majority of clinical and environmental isolates tested, and the RTX toxin produced by these strains catalyzes the covalent cross-linking of cellular actin.Keywords
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