BAL-INTRAV: a new non-toxic thiol for intravenous injection in arsenical poisoning
- 31 December 1946
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 41 (3) , 325-333
- https://doi.org/10.1042/bj0410325
Abstract
The following thiols were tested for toxicity and ability to diminish the toxicity of lewisite, [long dash]BAL (2:3-dimercaptopropanol), mer-captoacetate, mercaptosuccinate, mercaptoadipate, acetyl-mercaptosuccinate, dimercaptoadipate, glutathione, gluco-thiose and BAL-Intrav (2:3-dimercaptopropanol gluco-side). Toxicity diminished with increasing polarity of the molecule. The most effective therapeutic action was obtained with BAL. given intraven.Keywords
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