Drosophila p53: meeting the Grim Reaper
- 1 June 2000
- journal article
- editorial
- Published by Springer Nature in Nature Cell Biology
- Vol. 2 (6) , E100-E102
- https://doi.org/10.1038/35014093
Abstract
The recent discovery of a Drosophila orthologue of the p53 tumour suppressor promises new insights into the complex function, regulation and evolution of one of the most intensely studied human disease proteins.Keywords
This publication has 15 references indexed in Scilit:
- Comparative Genomics of the EukaryotesScience, 2000
- Drosophila p53 Binds a Damage Response Element at the reaper LocusCell, 2000
- Drosophila p53 Is a Structural and Functional Homolog of the Tumor Suppressor p53Cell, 2000
- Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP functionThe EMBO Journal, 2000
- Twenty years of p53 research: structural and functional aspects of the p53 proteinOncogene, 1999
- The p53 gene familyOncogene, 1999
- HAC-1, a Drosophila Homolog of APAF-1 and CED-4, Functions in Developmental and Radiation-Induced ApoptosisMolecular Cell, 1999
- Facing death in the fly: genetic analysis of apoptosis in DrosophilaTrends in Genetics, 1997
- Activation of thereaperGene during Ectopic Cell Killing inDrosophilaDevelopmental Biology, 1996
- The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia geneCell, 1995