Comparison of the Constricting Actions Produced by Serotonin and Prostaglandins on Isolated Sheep Umbilical Arteries and Veins

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Abstract
Sheep umbilical arteries and veins contracted to serotonin at concentrations less than those of prostaglandins. Also, serotonin produced a greater maximal contraction relative to the prostaglandins. PGF2Α and PGE2 were essentially equiactive in inducing contractions while PGE1, and PGF1Α were clearly less active than PGF2Α or PEG2