Structure and Hypotensive Effect of Flavonoid Glycosides inCitrus unshiuPeelings
- 1 April 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Agricultural and Biological Chemistry
- Vol. 49 (4) , 909-914
- https://doi.org/10.1080/00021369.1985.10866832
Abstract
An attempt was made to isolate hypotensive substances from a hot water extract of Citrus unshiu. Six flavonoid glycosides were isolated by repeated chromatography and gel filtration after extraction with butanol and treatment with lead subacetate. Their structures were established to be limocitrin 3-β-d-glucose (1), limocitrin-3-α-l-rhamnose (2), 3,6-di-C-glucosylapigenin (3), narirutin (4), rutin (5) and narcissin (6) by UV, 1-NMR and 13C-NMR spectroscopy and sugar analysis. Each component was intravenously injected into SHR-SP rats (1 mg/100g body weight), and 3 and 5 were found to lower their blood pressure. Among these compounds, 2 and 3 were a new flavonol and flavone glycoside, respectively.This publication has 3 references indexed in Scilit:
- The FlavonoidsPublished by Springer Nature ,1982
- 13C-NMR spectroscopy of biflavanoidsPhytochemistry, 1977
- The Systematic Identification of FlavonoidsPublished by Springer Nature ,1970