Stereo- and regio-controlled aldol synthesis using relative 1,2-asymmetric induction
- 1 January 1984
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 16,p. 1132-1134
- https://doi.org/10.1039/c39840001132
Abstract
Highly stereoselective addition of nucleophiles to α-methyl-β-methylene carbonyl compounds combined with the hydromagnesiation reactions of 2-alkyl-substituted 1,3-dienes affords a practical, efficient stereo- and regio-controlled aldol synthesis.Keywords
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