Effect of propranolol on the lower oesophageal sphincter in man
- 1 January 1980
- journal article
- Published by Informa Healthcare in Current Medical Research and Opinion
- Vol. 7 (2) , 91-95
- https://doi.org/10.1185/03007998009112032
Abstract
The effect of an intravenous dose (2 mg) of propranolol in the lower oesophageal sphincter was studied in 10 human volunteers. A hydraulic-capillary infusion manometric technique was used to measure the lower oesophageal sphincter pressure. A significant increase in sphincter pressure was recorded, together with increased amplitude and duration of oesophageal peristaltic activity. This study confirms the presence of specific beta-receptors in the lower oesophageal sphincter.Keywords
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