Failure of Cycloheximide To Induce Tyrosine Transaminase in the Anesthetized Rat
- 9 June 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 156 (3780) , 1376-1378
- https://doi.org/10.1126/science.156.3780.1376
Abstract
It was recently reported that cycloheximide, an inhibitor of protein synthesis, induces tyrosine transaminase in the liver of adrenalectomized rats. We have been unable to confirm this effect in the anesthetized animal and our data show that cycloheximide inhibits the induction caused by hydrocortisone in adrenalectomized rats or by stress in intact rats.Keywords
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