Cyclization of Nitriles as Synthetic Route to 2-and 3-Aminothiophenes

Abstract
This review is concerned with the preparation of 2-and 3-aminothiophenes, their hydrogenated derivatives, and fused systems by cyclization of nitriles. Substantial attention is given to the procedures for the synthesis of nitriles since they occur as intermediates in most reactions leading to aminothiophenes.

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