Mononuclear heterocyclic rearrangements. Part 15. Kinetic study of the amine-catalysed rearrangement of some Z-arylhydrazones of 3-benzoyl-5-phenylisoxazole into 2-aryl-4-phenacyl-5-phenyl-1,2,3-triazoles in acetonitrile and in benzene
- 1 January 1988
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 2
- No. 9,p. 1683-1686
- https://doi.org/10.1039/p29880001683
Abstract
The kinetics of the title reaction have been measured in the presence of n-butylamine, piperidine, triethylamine, and diazabicyclo[2.2.2]octane (DABCO). The reaction has also been studied in the presence of pairs of amines [butylamine (or piperidine) and triethylamine (or DABCO)] in benzene. The results confirmed the lower reactivity of isoxazole derivatives with respect to 1,2,4-oxadiazole derivatives (rate ratios ca. 10–3). The kinetic laws observed are accounted for by the ‘catalysis of catalysis’ mechanism.Keywords
This publication has 0 references indexed in Scilit: