HEAVY METAL CATALYSIS IN SMOOTH MUSCLE CONTRACTURE

Abstract
Cyanide, H2S, and CO applied to uterine and intestinal strips inhibit the tonic contractures caused by drugs and by chemical stimulants. The inhibition caused by CO is reversed during illumination provided sufficient O2 is present. The facts indicate that a heavy metal catalytic system is required in the response of smooth muscle to drugs and possibly also to autonomic and humoral stimuli.

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