FACTORS INFLUENCING THE PENETRATION OF THE SKIN BY CHEMICAL AGENTS
- 7 March 1948
- journal article
- Published by Wiley in Quarterly Journal of Experimental Physiology and Cognate Medical Sciences
- Vol. 34 (2) , 83-89
- https://doi.org/10.1113/expphysiol.1948.sp000923
Abstract
Using the common vesicants, mustard gas and lewisite, a study has been made of the factors influencing penetration of the skin. It has been concluded that penetration is facilitated by the presence of moisture on the skin and is hindered by the presence of fat. Defatting the surface of the skin will increase penetration, while active sweating with evaporation reduces penetration. The influence of a rise in external temperature is more complex, depending on whether the sweat is allowed to evaporate away and the degree of hyperæmia produced.Keywords
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