Studies on the Vitamin C Metabolism of Four Preschool Children1

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Abstract
Four preschool children were studied on various levels of ascorbic acid intake in an otherwise constant diet. After it was established that their tissues were saturated with vitamin C by checking their responses to test doses of 200 mg. of pure ascorbic acid, the level of intake was varied as follows: 115, 92, and 17 mg. were used for 1-week periods, and 66, 50, 43, and 31 mg. for 2-week periods. The 31 mg. level was repeated. Each period on a new level was followed by a test dose to recheck tissue saturation. The results of the study may be summarized as indicated below.