THE ACTION OF SODIUM CROMOGLYCATE ON ‘C’ FIBRE ENDINGS IN THE DOG LUNG
Open Access
- 1 September 1980
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 70 (1) , 11-13
- https://doi.org/10.1111/j.1476-5381.1980.tb10898.x
Abstract
The effect has been studied of sodium cromoglycate (SCG) on the activity of ‘C’ fibre sensory nerve endings in the canine lung. Pretreatment with SCG (100 μg/kg i.v.) reduced the excitation of these endings by capsaicin (10 μg/kg i.v.) for approximately 45 min. This property of SCG may explain its ability to suppress certain types of bronchoconstrictor responses in man.Keywords
This publication has 11 references indexed in Scilit:
- Reflex bronchoconstriction induced by capsaicin in the dogJournal of Applied Physiology, 1979
- The effects of histamine, acetylcholine and 5‐hydroxytryptamine on lung mechanics and irritant receptors in the dog.The Journal of Physiology, 1979
- SODIUM CROMOGLYCATE-INDUCED CHANGES IN THE DOSE-RESPONSE CURVE OF INHALED METHACHOLINE AND HISTAMINE IN ASTHMATIC-CHILDRENPublished by Elsevier ,1979
- Impulse activity in afferent vagal C-fibres with endings in the intrapulmonary airways of dogsRespiration Physiology, 1977
- Stimulation of ‘irritant’ receptors and afferent C-fibres in the lungs by prostaglandinsNature, 1976
- Search for Evidence of Lung Chemoreflexes in Man: Study of Respiratory and Circulatory Effects of Phenyldiguanide and LobelineClinical Science, 1972
- THE RELEASE OF PROSTAGLANDINS FROM LUNG AND OTHER TISSUESAnnals of the New York Academy of Sciences, 1971
- Role of the pulmonary arterial baroreceptors in the effects produced by capsaicin in the dogThe Journal of Physiology, 1964
- Mechanics of Respiration in Unanesthetized Guinea PigsAmerican Journal of Physiology-Legacy Content, 1958
- Receptors in the trachea and bronchi of the catThe Journal of Physiology, 1954