Effect of Dietary Phenylalanine and Tryptophan on Pineal and Hypothalamic Serotonin Levels.
- 1 December 1963
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 114 (3) , 718-721
- https://doi.org/10.3181/00379727-114-28779
Abstract
Summary Long-Evans rats were placed on diets containing 5% L-tryptophan or 7% L-phenylalanine or without supplements, when 4 weeks old and were sacrificed 5, 9, 12, or 19 days later. The high tryptophan diet led to a 250% increase in pineal and a nearly 100% increase in hypothalamic serotonin within 5 to 9 days. The high phenylalanine diet led to a 30% reduction in serotonin content in both tissues. These results are compared with those from whole brain.Keywords
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