THE ROLE OF THE RENIN-ANGIOTENSIN SYSTEM IN NORMOTENSIVE AND HYPERTENSIVE RATS WITH VARYING RENIN STATUS

  • 1 February 1987
    • journal article
    • research article
    • Vol. 285  (2) , 301-315
Abstract
We have investigated the relationship between the acute blood pressure lowering effect of captopril and renin status. Differences in renin status were induced by unilateral artery clipping combined with unilateral or bilateral nephrectomy in rats. The blood pressure lowering effect of captopril correlated very closely with plasma or aortic renin across a very wide range of renin levels.

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