Multiple Colorectal Adenomas — Is Their Number Up?
- 27 February 2003
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 348 (9) , 845-847
- https://doi.org/10.1056/nejme030002
Abstract
In this issue of the Journal, Sieber et al.1 report that up to 30 percent of cases of multiple colorectal adenomas (15 to 100 adenomas) might be linked to biallelic mutations in the MYH gene. What are the implications of this finding for the diagnosis and management of this disease?Isolated adenomatous polyps are found in the colon in many persons, especially after 50 years of age. Since 5 to 10 percent of these lesions undergo malignant transformation over the course of several years, the endoscopist will reduce the risk of cancer by removing them. In the rare instances in . . .Keywords
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