Growth of Cancerous and of Embryonic Tissues Stratified in the Ultra-Centrifuge.
- 1 December 1936
- journal article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 35 (3) , 468-473
- https://doi.org/10.3181/00379727-35-9020c
Abstract
The cells of carcinoma tissue, after 30 minutes of centrifugalizatioii in an ultracentrifuge at a displacement pull of 400,000 times that of gravity, show little trace of stratification of contents. Apparently the cytoplasni of such cells is of the consistency of a stiff gel. Such cells centrifuged for 20 minutes grew as readily as non-centrifuged cancer cells when implanted in young rats. The cells in lits of embryonic body-wall centrifuged for 12 and for 20 minutes respectively, although having their contents markedly stratified by the treatiiient, resumed growth when implanted subcutaneously in young rats, developing usually into hair-filled cysts of skin but occasionally into cartilage and bone. These results were prohably due to the misplacement of embryonic tissues rather than to changes induced by centrifugalization.Keywords
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