The effect of two phenothiazines and a barbiturate on extinction-induced rate increase of a free operant.

1 October 1962

journal article
Published by American Psychological Association (APA) in Journal of Comparative and Physiological Psychology

Vol. 55 (5) , 714-718
https://doi.org/10.1037/h0042626

Abstract

Rats were first trained to bar press for water reward. Then, after injection of 1 of 3 doses of either phenobarbital, thioridazine, or chlorpromazine, each animal received a 10-min. session with regular reinforcement, followed by extinction. The extinction inflection ratio (increase in response early in extinction) bore an inverse relation to dose, but was equivalent for all drugs. However phenobarbital produced greater ataxia than did the phenothiazines. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

Keywords

RAT/DRUG EFFECTS IN
PSYCHOPHARMACOLOGY
BARBITURATE
PHENOTHIAZINES &
&
THIORIDAZINE
EXTINCTION LEARNING
PHENOTHIAZINES
PHENOBARBITAL
EXTINCTION (SEE ALSO FORGETTING
OF OPERANT
CHLORPROMAZINE
INHIBITION
LEARNING)
EXTINCTION OF OPERANT

This publication has 0 references indexed in Scilit: