Distribution of HLA‐B alleles in nasopharyngeal carcinoma patients and normal controls in Thailand
- 1 March 2002
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 59 (3) , 223-225
- https://doi.org/10.1034/j.1399-0039.2002.590308.x
Abstract
HLA‐B frequencies in 54 unrelated nasopharyngeal carcinoma (NPC) patients and 49 healthy random controls in Thailand were investigated by direct DNA sequencing. Similar to previous reports in Chinese NPC patients, HLA‐B*4601 was observed at a greater frequency in patients (21/54 (40%)) compared to controls (7/49 (14%). An increase in HLA‐B*51012 was also demonstrated. B*51012 was present in 6/54 (11%) NPC patients but was not observed (0%) in controls. B*44032 was associated with a decreased risk. Five out of 54 (9%) NPC patients had B*44032 compared to 14/49 (29%) in the control group.Keywords
This publication has 16 references indexed in Scilit:
- Novel HLA-B alleles associated with antigens in the 8C CREGTissue Antigens, 2001
- Diversity of alleles encoding HLA-B40: relative frequencies in United States populations and description of five novel allelesHuman Immunology, 2000
- Association between microsatellites within the human MHC and nasopharyngeal carcinomaInternational Journal of Cancer, 1997
- Human Leucocyte Antigens and Nasopharyngeal CarcinomaClinical Science, 1996
- The inter-locus recombinant HLA-B*4601 has high selectivity in peptide binding and functions characteristic of HLA-C.The Journal of Experimental Medicine, 1996
- Linkage of a nasopharyngeal carcinoma susceptibility locus to the HLA regionsNature, 1990
- HLA‐A, ‐B, and ‐DR antigens in North African patients with nasopharyngeal carcinomaTissue Antigens, 1983
- HLA and nasopharyngeal carcinoma in North American CaucasoidsTissue Antigens, 1983
- HLA antigens in East African black patients with Burkitt's lymphoma or nasopharyngeal carcinoma and in controls: A pilot studyHuman Immunology, 1982
- PROBABLE IDENTIFICATION OF AN HL-A SECOND-LOCUS ANTIGEN ASSOCIATED WITH A HIGH RISK OF NASOPHARYNGEAL CARCINOMAThe Lancet, 1975