LOWER GASTROINTESTINAL SIDE-EFFECTS OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS
- 1 January 1981
- journal article
- research article
- Vol. 8 (6) , 952-954
Abstract
Nonsteroidal antiinflammatory drugs (NSAID) [acetylsalicyclic acid, phenylbutazone, indomethacin, ibuprofen, naproxen] can cause upper gastrointestinal (GI) blood loss and reactivation of peptic ulcer disease. Three patients in whom NSAID ingestion was temporally associated with serious lower GI disease, including bleeding in 2 patients are described. These cases suggest an association between NSAID and activation of serious lower GI disease.This publication has 4 references indexed in Scilit:
- IbuprofenAnnals of Internal Medicine, 1979
- Gastrointestinal microbleeding after aspirin and naproxenClinical Pharmacology & Therapeutics, 1978
- Gastro-Intestinal Blood Loss during Administration of Indoprofen, Aspirin and IbuprofenJournal of International Medical Research, 1977
- The mode of action of aspirin and similar compoundsJournal of Allergy and Clinical Immunology, 1976