Two mutant low-density-lipoprotein receptors in Afrikaners slowly processed to surface forms exhibiting rapid degradation or functional heterogeneity
- 15 October 1988
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 255 (2) , 411-415
- https://doi.org/10.1042/bj2550411
Abstract
Two distinct mutant low-density-lipoprotein receptors in South African Afrikaners exhibit retarded posttranslational processing to mature forms. One mutation gives rise to cell-surface receptors that are subject to abnormally rapid degradation, whereas the other is associated with a functionally heterogeneous surface population degraded at a normal rate.This publication has 21 references indexed in Scilit:
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