Sequence-Specific Cleavage of RNA Using Macrocyclic Lanthanide Complexes Conjugated to Oligonucleotides: A Structure Activity Study
- 1 July 1997
- journal article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 16 (7-9) , 1357-1368
- https://doi.org/10.1080/07328319708006187
Abstract
A series of lanthanide complexes were synthesized and conjugated to an oligodeoxynucleotide. Sequence-specific cleavage of a complementary RNA by the conjugates was performed and results are discussed in terms of structure of the complexes.Keywords
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