Thalidomide inhibits lipoarabinomannan-induced upregulation of human immunodeficiency virus expression
- 1 December 1995
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 39 (12) , 2807-2809
- https://doi.org/10.1128/aac.39.12.2807
Abstract
Mycobacterium tuberculosis accelerates the progression of human immunodeficiency virus type 1 (HIV-1) infection. The results of this study, which show that thalidomide inhibits the upregulation of HIV-1 expression in U1 cells stimulated with mycobacterial lipoarabinomannans, support the rationale behind conducting controlled trials of this immunodeficiency agent with patients dually infected with HIV-1 and M. tuberculosis.Keywords
This publication has 20 references indexed in Scilit:
- Thalidomide Inhibits Tumor Necrosis Factor- Production by Lipopolysaccharide- and Lipoarabinomannan-Stimulated Human Microglial CellsThe Journal of Infectious Diseases, 1995
- Mycobacterium tuberculosis enhances human immunodeficiency virus-1 replication by transcriptional activation at the long terminal repeat.Journal of Clinical Investigation, 1995
- Thalidomide as Treatment of Refractory Aphthous Ulceration Related to Human Immunodeficiency Virus InfectionClinical Infectious Diseases, 1995
- Human Immunodeficiency Virus And Mycobacterium avium Complex Coinfection Of Monocytoid Cells Results In Reciprocal Enhancement Of MultiplicationThe Journal of Infectious Diseases, 1995
- Phagocytosis of Mycobacterium tuberculosis modulates human immunodeficiency virus replication in human monocytic cellsJournal of General Virology, 1994
- Mycobacterium tuberculosis Induces Expression of P-Glycoprotein in Promonocytic U1 Cells Chronically Infected with HIV Type 1Biochemical and Biophysical Research Communications, 1994
- Effect of isoniazid prophylaxis on incidence of active tuberculosis and progression of HIV infectionThe Lancet, 1993
- Enhanced susceptibility of blood monocytes from patients with pulmonary tuberculosis to productive infection with human immunodeficiency virus type 1.The Journal of Experimental Medicine, 1993
- Influence of Tuberculosis on Human Immunodeficiency Virus (HIV-1): Enhanced Cytokine Expression and Elevated 2-Microglobulin in HIV-1-Associated TuberculosisThe Journal of Infectious Diseases, 1993
- Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.The Journal of Experimental Medicine, 1991